Avene Hyaluron Activ B3 Multi-Intensive Cream 40 ml

Hyaluron Activ B3 – multi-intensive night cream

The Eau Thermale Avène brand comes with a revolutionary new approach in the fight against wrinkles – dermocosmetic care with concentrated hyaluronic acid in combination with 6% niacinamide , which acts against the cause of aging*, smoothes wrinkles and strengthens the skin. The company, in collaboration with renowned anti-aging expert Professor Jean-Marc Lemaitre, focused on cellular senescence, the final stage of cellular aging. Each cell gradually ages, ceases to be active, fulfills its function and becomes senescent. Scientists have called these zombie cells because they start to secrete a specific secretome (SMS – Senescence-Messaging-Secretome) through which they contaminate the surrounding healthy skin cells, spreading and thus accelerating skin aging. Cellular senescence is 'contagious'.

The Hyaluron Activ B3 range directly targets the cause of aging , cellular senescence, protects cells, extends their lifespan by up to 50%** and slows skin aging. At least 92% of the ingredients are of natural origin. It is vegan and free of controversial substances.

The multi-intensive night cream is the only one that does not act directly on cellular senescence . It contains a lower concentration of 2% niacinamide, which restores the skin's protective barrier so that the skin retains water better. This care is the cherry on top of the whole range. Vitamin A is the substance with the greatest rejuvenating capacity, it is the engine of cellular youth. This rich night cream reinforces the skin's natural regeneration processes while you sleep. You'll wake up in the morning with glowing, smooth skin.

Use every evening on dry, perfectly cleansed skin. If you have very sensitive skin or have unpleasant stinging or other discomfort, extend the interval between individual applications until the skin gets used to the retinaldehyde. Ideally, it is used once every other day. The product has a delicate fragrance and a light coloring due to the natural coloring of the active substances - retinaldehyde and haritaki extract.

Main active ingredients:

6% niacinamide

Precise concentration of clinically proven niacinamide that delays the onset of cellular senescence, slows the spread of aging in the skin, reduces wrinkles and fine lines, improves skin elasticity, reduces age spots and alleviates oxidative stress.

Pure and natural hyaluronic acid HMW and precise fragment HAF120

Hyaluronic acid is the main and basic component of the skin. If its concentration decreases, the skin sags and wrinkles appear. High molecular weight hyaluronic acid (HMW) plumps the skin and hydrates it on the surface, while low molecular weight hyaluronic acid (HAF120) works deep down, stimulating its natural and anti-wrinkle production.

Haritaki extract

Extracted from the fruit of longevity, which the Buddha himself holds in his hand. Protects hyaluronic acid and prevents its loss from the skin. After only 8 hours, 10 times more hyaluronic acid remains in the skin.***

RETINAL

Retinal (retinaldehyde) is less known than retinol, but 10 times more effective**** because it is a direct precursor (usable store) of retinoic acid, which is the form of vitamin A that the skin needs. Retinal stimulates cell renewal* and activates collagen synthesis.

97% of the ingredients are of natural origin.

* In vitro test.

** HT Kang et al., Aging Cell (2006) 5, pp. 423–436.

*** Pharmacological evaluation of HA content in skin, in vitro test, 2021.

**** Biochem J. (1990) 268, 371–378, Printed in Great Britain, Retinol and retinal metabolism. Relationship to differentiation state of cultured human keratinocytes. Siegenthaler G. et al.

Composition

Avene thermal water (avene aqua). Caprylic/capric triglycerides. Glycerin. Squalane. Butyrospermum parkii (shea butter) (butyrospermum parkii butter). Carthamus tinctorius seed oil (safflower seed oil) (Carthamus tinctorius seed oil). pentaerythritol tetracaprylate/tetracaprate. Cetearyl alcohol. Behenyl alcohol. Niacinamide. C20-22 alkyl phosphate. C20-22 alcohols. Retinal. Sodium hyaluronate. Terminalia chebula fruit extract. Adenosine. Senegal acacia gum. Cetearyl glucoside. Perfume (perfume). Helianthus annuus seed oil (helianthus annuus seed oil). Red 33 (ci 17200). Sodium benzoate. Sodium hydroxide. Tocopherol. Tocopheryl glucoside. Water (aqua). Xanthan gum.

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